Post-PCI: QFR independently predicts adverse events after stent implantation

Simone Biscaglia and co-authors published in the JACC the HAWKEYE study that aimed to assess the predictive value of post-percutaneous coronary intervention (PCI) quantitative flow ratio (QFR) measurements for clinical outcomes in patients with successful PCI. The international multicenter prospective study included 602 patients who underwent complete revascularization, with 751 vessels analyzed. Post-PCI QFR values were significantly lower in vessels experiencing adverse events during follow-up. Receiver-operating characteristic curve analysis identified a post-PCI QFR cutoff of ≤0.89 as predictive of adverse events, with a 3-fold increase in risk associated with this threshold. This study highlights the potential of post-PCI QFR measurements in predicting subsequent adverse events following successful revascularization procedures.