In daily clinical routine, QFR promises good diagnostic agreement as compared to both iFR and RFR.

Reading time: 5 mins
Written on: March 5, 2024
Dr. J Stader from the University Hospital Leipzig in Germany, under the supervision of Dr. K Lenk, published this prospective, single-center study, which includes 102 patients with an indication for elective coronary angiography in the Catheterization and Cardiovascular Interventions Journal.
In this population, QFR was compared with the instantaneous wave-free ratio (iFR) or resting full cycle ratio (RFR). The AuC for all measurements was 0.93 for QFR compared to iFR or RFR. QFR requires less time compared to iFR or RFR. The median use of contrast was similar. However, QFR diagnostics required less radiation: the median dose area product was 307 cGycm2 compared to 599 cGycm2 for iFR or RFR. The authors concluded that QFR correlates with iFR or RFR and is associated with shorter procedure times and reduced radiation dose.

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