In the field of coronary revascularization, where identifying reversible myocardial ischemia is paramount, FFR and iFR are standard but underutilized due to various limitations. QFR, an angiography-derived method, emerges as a potential game-changer, providing functional assessment without additional wires or hyperemic agents and showcasing a shorter measurement time than invasive methods. In conclusion, the study, aligning with ongoing trials, suggests that a QFR-guided strategy could simplify, enhance safety, and cost-effectively guide revascularization decisions. Furthermore, the findings position QFR as a promising tool to boost the adoption of physiology-based revascularization in routine clinical practice.
Hwang D. et al, published in the Journal American Heart Association an intriguing study that explores the diagnostic performance of QFR, comparing it to FFR and iFR as reference standards, with additional evaluation against CFR. Notably, QFR demonstrated excellent correlation and diagnostic performance with both FFR and iFR, outperforming iFR in discriminant function. While QFR’s diagnostic accuracy was higher with FFR, it remained good with iFR, showcasing its versatility across different physiological indices.
