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Silent Myocardial Perfusion abnormalities detected by Stress CVMR in Antiphospholipid Syndrome

The team of Sophie Mavrogeni, Onassis Cardiac Surgery Center in Athens has carried out a case-control study in patients with the Antiphospholipid Syndrome (APS). Using the Medis Suite MR solution, they measured the myocardial perfusion index (MPRI, defined as the median myocardial blood flow MBF during stress divided by the MBF at rest), as well as Late Enhancement LGE, in a total of 44 consecutive APS patients without prior cardiac disease and 44 age/gender-matched controls. They concluded that abnormal MPRI and LGE are common in asymptomatic APS patients, independently so of any APS-related and classic CVD risk factors, or coronary angiography findings in cases with LGE. Stress-CMR is a valuable tool to detect silent myocardial ischemia and fibrosis in APS.

For further read: J Clin Med 2019,8,1084; doi: 10.3390/jcm8071084

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