Martin Sejr-Hansen and colleagues from Aarhus university published this iSTEMI substudy. They compared the QFR based on acute setting angiograms with the QFR, FFR and iFR in the staged setting as reference. The mean QFR in the acute setting was 0.82 and the values in the staged setting for QFR, FFR and iFR were 0.80, 0.81 and 0.91, respectively. The classification agreement of acute and staged QFR was 93%, with FFR as reference 84%, and 74% with iFR as reference.
Their conclusion: Acute QFR showed a very good diagnostic performance with staged QFR as reference, a good diagnostic performance with staged FFR as reference, and a moderate diagnostic performance with staged iFR as reference.
Catheter Cardiovasc Interv 2019; doi:10.1002/ccd.28208